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SELECTA BIOSCIENCES INC: Entering into a Material Definitive Agreement, Creating a Direct Financial Obligation or Obligation Under an Off-Balance Sheet Arrangement of a Holder, Other Events, Financial Statements and Exhibits (Form 8-K)

Section 1.01 Entering into a Material Definitive Agreement.

On March 21, 2022, Selecta Biosciences, Inc. (the "Company") entered into a
Second Amendment to Loan and Security Agreement (the "Second Amendment"),which
amended that certain Loan and Security Agreement, dated August 31, 2020, between
the Company, Oxford Finance LLC, as collateral agent and as a lender, and
Silicon Valley Bank, as a lender (as amended by that certain First Amendment to
Loan and Security Agreement, dated September 7, 2021, and as further amended by
the Second Amendment, the "Loan Agreement").

The Second Amendment, among other things, extends the date on which amortization
payments in respect of the term loan borrowed under the Loan Agreement (the
"Term Loan") will commence by twelve months to April 1, 2023. Thereafter,
amortization payments will be paid monthly in equal installments of principal
and interest to fully amortize the outstanding principal over the remaining term
of the Term Loan, subject to recalculation upon a change in the prime rate.

The foregoing description of the Second Amendment is a summary, and is qualified
in its entirety by reference to the Second Amendment which is filed herewith as
Exhibit 10.1, and is incorporated herein by reference.


Item 2.03 Creation of a Direct Financial Obligation or Obligation Under an Off-Balance Sheet Arrangement of a Registrant.

The information regarding the Term Loan set forth in Section 1.01 of this Current Report on Form 8-K is incorporated by reference into this Section 2.03.

Section 8.01 Other Events.

The Company believes that its current cash, cash equivalents, and restricted
cash as of the date of this filing will enable it to fund its current planned
operations into the fourth quarter of 2023.


Item 9.01 Financial statements and supporting documents.

(d) Exhibits

    Exhibit
      No.                                            Exhibit Description

      10.1                Second Amendment to Loan and Security Agreement, dated March 21, 2022,
                        between Selecta Biosciences, Inc., Oxford Finance

LLC, as warranty agent and

                        as a lender, and Silicon Valley Bank, as a lender.
      104               Cover Page Interactive Data File (embedded within

the Inline XBRL document)

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